About Me

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Scottsdale, Arizona, United States
Angela M. DeRosa DO, MBA, CPE graduated from the Chicago College of Osteopathic Medicine in 1995. She went on to do an Internal Medicine Residency with a fast track emphasis in Women’s Health at Lutheran General Hospital. After her residency, she became the Director of Women’s Health Services and Education at Lutheran General Hospital. After two years of practice she started a full time career as the West Coast Senior Medical Director with Procter and Gamble Pharmaceuticals. There she worked on women's health product development, research and marketing. Seven years after starting this position, Dr. DeRosa decided to pursue other clinical endeavors. Dr. DeRosa is a nationally recognized internist and women’s health expert. Her clinical focus is on revitalizing the physician-patient relationship; striving to provide the highest quality of care to her patients in a warm compassionate environment.

Tuesday, November 19, 2013

Does Testosterone Really Lead to Heart Attacks in Men?

Testosterone Leads to Heart Attacks? 

Not so fast, says Dr. Angela DeRosa, DO, MBA, CPE. It was misunderstandings, misreporting of results and media hype that launched the panic over the WHI study on women and HRT in 2002, and the negative impact for women’s health has lasted to this day. 

This study linking testosterone to heart attacks makes the same mistakes and in my opinion they are committing reporting malpractice. Here is what men need to know…

According to Dr. DeRosa, an internal medicine doctor and hormonal health specialist, this is NOT a randomized controlled study. They do not match the patients properly, and they are not accounting for many variables that may already exist in this population comparison.The 26-29 percent increase quoted is a relative risk, NOT an absolute risk. 

In the original WHI study, the media reported that there was a 26 percent increase for risk of developing breast cancer when using hormone replacement therapy – specifically, this occurred in the Prempro trial. In reality, this number wasn’t statistically significant. Here’s why: the percentage was based on EIGHT more women having breast cancer in the Prempro arm. 

This study linking testosterone to heart attacks does the same thing. Once again, the media is looking at a small number of people that’s not statistically significant and making the larger number the report, and it’s again spreading fear and misinformation.

This testing was done on an older male population, which will naturally have a higher incidence of Coronary Artery Disease. As we age, plaque builds up in our arteries. For some people, it’s never a problem. For others, it advances to Coronary Artery Disease. The testosterone supplementation is not causing the condition: the groundwork has already been laid by years of lifestyle, usually poor diet, alcohol and tobacco use, or other variables.

Testosterone supplementation is usually prescribed for use in otherwise healthy males who are experiencing abnormal rates of testosterone decline. Catch it early, and we reduce the risk for developing heart disease, some cancers and other health conditions. 

This is a terrible leap to make these claims...once again. Let’s hope they don’t have the lasting negative impact irresponsible reporting and misinterpretations of data associated with the WHI 2002 study. If you’re still concerned, see your doctor.


Dr. Angela DeRosa, DO, MBA, CPE is a warrior for women, advocating for better understanding of women's health issues and the importance of hormonal balance to overall good health. She's warm and funny with just the right amount of wacky, but make no mistake, Dr. DeRosa knows her stuff. She has a gift for breaking down complex medical conditions into easily understandable terms. She uses media outlets to cut through misinformation and misconceptions and get to the heart of common health problems like thyroid disease, obesity, birth control, problems in the bedroom, romance killers, and menopause and how they impact our quality of life.
She is nicknamed Dr Hot Flash because she went through menopause in her early 30s and now devotes her work to help other women not feel so hopeless and scared about how they age. She holds quarterly events called "Hormonal Happy Hours" where women can attend and talk about sex, health, life in a comfortable and fun environment. www.derosamedical.com